L A U T E R B U R G . R E S E A R C H . G R O U P

G R O U P . M E M B E R S

• Identification and Quantitation of small molecules in a biological fluid
• Metabolomics from sample preparation to data acquisition and analysis
• Assessment of Mitochondrial Function in vivo (Breath Tests)
• Xenobiotic Induced Alterations in Mitochondrial Function
• Effects of Chronic Ethanol Administration on MtDNA Oxidation

S E L E C T E D . P U B L I C A T I O N S

Chtioui H, Semela D, Ledermann M, Zimmermann A, Dufour JF. Expression and activity of the cytochrome P450 2E1 in patients with nonalcoholic steatosis and steatohepatitis. Liver Int. 2007 Aug;27(6):764-71.

Chtioui H, Zimmermann A, Dufour JF. Unusual evolution of posterior reversible encephalopathy syndrome (PRES) one year after liver transplantation. Liver Transpl. 2005 May;11(5):588-90.

Russmann S, Junker E, Lauterburg BH. Remethylation and transsulfuration of methionine in cirrhosis: studies with L-[H3-methyl-1-C]methionine. Hepatology. 2002;36:1190-6.

Russmann S, Lauterburg BH, Helbling A. Kava hepatotoxicity. Ann Intern Med 2001; 135: 68-69.

Sonderegger T, Betticher DC, Cerny T, Lauterburg BH. Pharmacokinetics of 2-chloro-2'-deoxyadenosine administered subcutaneously or by continuous intravenous infusion. Cancer Chemother Pharmacol, 46: 40-42, 2000.

Grattagliano I, Vendemiale G, Deiss VB, Junker E, Lauterburg BH. Effect of oral and intravenous S,N-diacetylcysteine monoethyl ester on circulating and hepatic sulfhydrils in the rat. J Pharmacol Exptl Ther, 294:155-9, 2000.

Peter C, Hongwan D, Küpfer A, Lauterburg BH. Pharmacokinetics and organ distribution of intravenous and oral methylene blue. Eur J Clin Pharmacol, 56: 247-250, 2000.

Grattagliano I, Vendemiale G, Lauterburg BH. Reperfusion injury of the liver: Role of mitochondria and protection by glutathione ester. J Surg Res, 86:2-8, 1999.

Marthaler NP, Visarius TM, Küpfer A, Lauterburg BH. Increased urinary losses of carnitine during ifosfamide chemotherapy, Cancer Chemother Pharmacol 44:170-172, 1999.

Visarius TM, Stucki JW, Lauterburg BH. Inhibition and stimulation of long chain fatty acid oxidation by chloroacetaldehyde and methylene blue in rats, J Pharmacol Exptl Ther, 289:820-824, 1999.

Bernhard MC, Junker E, Hettinger A, Lauterburg BH. Time course of total cysteine, glutathione and homocysteine in plasma of patients with chronic hepatitis C treated with interferon-? with and without supplementation of N-acetylcysteine. J. Hepatology, 28: 751-755, 1998.

Visarius TM, Bähler H, Küpfer A, Cerny Th, Stucki J, Lauterburg BH. Thiodiglycolic acid is excreted in humans receiving ifosfamide chemotherapy and inhibits mitochondrial function in rats. Drug Metab Dispos 26:193-196, 1998.

Visarius TM, Stucki JW, Lauterburg BH. Stimulation of respiration by methylene blue in rat liver mitochondria. FEBS Letters 412: 157-160, 1997.

Helbling B, von Overbeck J, Lauterburg BH. Decreased release of glutathione into the systemic circulation of patients with HIV infection. Eur J Clin Invest, 26:38-44, 1996.

Witschi A, Schwarzenbach FA, Lauterburg BH. Mitochondrial function assessed by in vivo decarboxylation of a-ketoisocaproate is normal in patients with promary biliary cirrhosis. Interntl Hepatology Commun, 3:316-321, 1995.

Wieland P, Lauterburg BH. Oxidation of mitochondrial proteins and DNA following administration of ethanol. Biochem Biophys Res Commun, 213:815-819, 1995.